Buffalo Bills

Jordan Hancock CB IR

Injured Reserve

Hancock has been on IR since late September while recovering from a hamstring injury he suffered in Week 2 versus Detroit. The cornerback had his 21-day practice window opened Wednesday, and if he isn't activated in that time frame, he will remain on IR for the rest of the 2026 campaign.

Reported: Nov 04

Zane Durant DT IR

Injured Reserve

Durant compiled six total tackles (three solo) during the preseason, but he appears to have picked up an undisclosed injury at some point along the way. As a result, the 2026 fifth-round pick will be forced to miss at least four regular-season contests to open his rookie campaign.

Reported: Aug 31

Demetrius Flannigan-Fowles LB IR

Injured Reserve

ir

Reported: Aug 19

Joshua Palmer WR IR

Injured Reserve

ir

Reported: Nov 09

Dorian Strong CB O

Out

nfi-r

Reported: Sep 08

Mike Danna DE O

Out

inactive

Reported: Nov 09

Ar'maj Reed-Adams G O

Out

inactive

Reported: Nov 01

Jude Bowry OT O

Out

inactive

Reported: Oct 18

Jalon Kilgore S O

Out

inactive

Reported: Nov 09

Skyler Bell WR O

Out

inactive

Reported: Nov 09

Tyrell Shavers WR O

Out

Shavers will remain sidelined for at least one more game as he continues to work his way back from a torn ACL. The wide receiver returned to practice in late October, and he could be activated prior to the team's Week 10 matchup with the Jets.

Reported: Nov 09

Connor McGovern C Q

Questionable

questionable

Reported: Nov 11

Christian Benford CB Q

Questionable

Benford injured his wrist in Monday night's win over the Vikings but was able to return to the contest. Across seven starts this season, he has 31 tackles (21 solo) and seven pass breakups on 89 percent of the defensive snaps.

Reported: Nov 11

Dee Alford CB Q

Questionable

questionable

Reported: Nov 03

Te'Cory Couch CB Q

Questionable

Couch was a practice-squad elevation for Week 4. He was slated to potentially pick up some work on defense with Christian Benford (toe) inactive, but now Couch is probably done for the day. With that said, Couch's likely absence will primarily impact Buffalo's special-teams unit.

Reported: Oct 04

Landon Jackson DE Q

Questionable

questionable

Reported: Oct 13

Michael Hoecht DE Q

Questionable

Hoecht tore his right Achilles during the Bills' Week 9 contest against the Chiefs. That was just his second appearance of the 2025 regular season after he missed the first six games while serving a suspension. He's drawn praise from his teammates and coaching staff for his approach to his rehab, and Hoecht is hoping to be available for the Bills' regular-season opener against the Texans on Sunday, Sept. 13.

Reported: Aug 04

Ed Oliver DT Q

Questionable

questionable

Reported: Oct 20

Greg Gaines DT Q

Questionable

Gaines didn't suit up for the Week 8 win over the Ravens. While he did practice in a limited capacity Saturday, he still isn't ready to get back on the field. The 30-year-old has appeared in six games during the 2026 campaign, amassing 11 total tackles (three solo) and one fumble recovery.

Reported: Nov 09

T.J. Sanders DT Q

Questionable

questionable

Reported: Oct 28

Ben VanSumeren FB Q

Questionable

VanSumeren has fully recovered from the torn patella tendon he suffered last September with the Eagles. The 26-year-old is expected to serve as the Bills' primary fullback during the upcoming campaign.

Reported: Aug 05

Bradley Chubb LB Q

Questionable

questionable

Reported: Oct 28

Joe Andreessen LB Q

Questionable

questionable

Reported: Oct 29

TJ Parker LB Q

Questionable

questionable

Reported: Oct 28

Terrel Bernard LB Q

Questionable

questionable

Reported: Aug 25

Alec Anderson OT Q

Questionable

Anderson is dealing with an ankle injury that caused him to miss practice Thursday and Friday. He was able to log a limited session Saturday, but that won't be enough for him to suit up for Monday Night Football. Austin Corbett figures to start at left guard in Anderson's place.

Reported: Nov 09

Chase Lundt OT Q

Questionable

Lundt ended the 2025 season with just eight total snaps for the Bills. The 2025 sixth-rounder is battling with Jude Bowry, Travis Clayton, Nick Broeker and Austin Corbett for a chance at the 53-man roster. With the Bills keeping nine offensive linemen on the initial 2025 roster, two of the four players will likely not make the 2026 cut.

Reported: Aug 14

Dion Dawkins OT Q

Questionable

Dawkins injured his ribs in the Week 8 win over the Ravens and didn't practice during the week ahead of Monday's meeting with Minnesota. While the veteran carried a questionable tag, suggesting there was a chance he would suit up, he won't be on the field, meaning Josh Allen will be without his top protector.

Reported: Nov 09

Jedrick Wills Jr. OT Q

Questionable

questionable

Reported: Sep 05

Spencer Brown OT Q

Questionable

questionable

Reported: Nov 11

Ray Davis RB Q

Questionable

Davis received the day off while he was feeling under the weather, but so long as he's able to get back on the practice field Friday, he should avoid taking a designation into Sunday's game against the Ravens. While handling a backup role behind lead back James Cook this season, Davis has carried just five times for 12 yards to go with three receptions for 40 yards through Buffalo's first six contests.

Reported: Oct 29

Ty Johnson RB Q

Questionable

Johnson will have an extra day to rest up this week, as the Bills host the Vikings on Monday night. Buffalo's preferred pass-catching back, Johnson has rushed six times for just 10 yards through six games this season, but he has caught all 15 of his targets for 174 yards.

Reported: Nov 05

Cole Bishop S Q

Questionable

Bishop was listed as a limited practice participant on all three injury reports due to a groin injury, and his status for Thursday's game may not be officially known until about 90 minutes before the 8:15 p.m. ET kickoff. Damar Hamlin would likely draw the start at safety alongside C.J. Gardner-Johnson if Bishop is not cleared to play.

Reported: Sep 16

Sam Franklin Jr. S Q

Questionable

questionable

Reported: Nov 06

Dalton Kincaid TE Q

Questionable

Kincaid began last week with a limited session due to a chest issue, but was able to suit up for Monday night's win over the Vikings while seeing the field on 50 percent of the Bills' snaps on offense. In the process, the tight end caught all three of his targets for 28 yards. It's unclear if Kincaid's ankle injury occurred versus Minnesota or is something that occurred Wednesday, but either way added context regarding his status for this weekend's game against the Jets will arrive via Thursday's injury report.

Reported: Nov 11

DJ Moore WR Q

Questionable

Moore has managed an AC joint sprain for most of the season, typically practicing in a non-contact jersey. He'll likely be ready for Monday's game at Minnesota, coming off a 4-82-1 receiving line (seven targets) in last week's 36-10 win over Baltimore.

Reported: Nov 06

Keon Coleman WR Q

Questionable

Coleman is on the injury report for the first time since Week 4, listed as a limited participant Thursday and Friday due to a shoulder injury. There's been no indication it's serious, so Coleman seems on track to play Monday night at Minnesota. Fellow Bills wideout DJ Moore (shoulder) also is gearing up to play.

Reported: Nov 06

Khalil Shakir WR Q

Questionable

Since making an appearance preseason Week 1 on Aug. 15, Shakir has been sidelined due to an undisclosed injury, including no activity at Tuesday's practice. The Bills will post their first Week 1 injury report next Wednesday, and how he's listed then will provide a sense for his status ahead of the regular-season opener.

Reported: Sep 02

Phidarian Mathis DT SUS

Suspension

reserve-sus

Reported: Aug 19

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

Reported: Nov 01

Christian Benford CB Q

Questionable

Benford injured his wrist in Monday night's win over the Vikings but was able to return to the contest. Across seven starts this season, he has 31 tackles (21 solo) and seven pass breakups on 89 percent of the defensive snaps.

Connor McGovern C Q

Questionable

questionable

Dalton Kincaid TE Q

Questionable

Kincaid began last week with a limited session due to a chest issue, but was able to suit up for Monday night's win over the Vikings while seeing the field on 50 percent of the Bills' snaps on offense. In the process, the tight end caught all three of his targets for 28 yards. It's unclear if Kincaid's ankle injury occurred versus Minnesota or is something that occurred Wednesday, but either way added context regarding his status for this weekend's game against the Jets will arrive via Thursday's injury report.

Spencer Brown OT Q

Questionable

questionable

Alec Anderson OT Q

Questionable

Anderson is dealing with an ankle injury that caused him to miss practice Thursday and Friday. He was able to log a limited session Saturday, but that won't be enough for him to suit up for Monday Night Football. Austin Corbett figures to start at left guard in Anderson's place.

Dion Dawkins OT Q

Questionable

Dawkins injured his ribs in the Week 8 win over the Ravens and didn't practice during the week ahead of Monday's meeting with Minnesota. While the veteran carried a questionable tag, suggesting there was a chance he would suit up, he won't be on the field, meaning Josh Allen will be without his top protector.

Greg Gaines DT Q

Questionable

Gaines didn't suit up for the Week 8 win over the Ravens. While he did practice in a limited capacity Saturday, he still isn't ready to get back on the field. The 30-year-old has appeared in six games during the 2026 campaign, amassing 11 total tackles (three solo) and one fumble recovery.

Jalon Kilgore S O

Out

inactive

Joshua Palmer WR IR

Injured Reserve

ir

Mike Danna DE O

Out

inactive

Skyler Bell WR O

Out

inactive

Tyrell Shavers WR O

Out

Shavers will remain sidelined for at least one more game as he continues to work his way back from a torn ACL. The wide receiver returned to practice in late October, and he could be activated prior to the team's Week 10 matchup with the Jets.

Alec Anderson OT Q

Questionable

Anderson didn't practice Thursday or Friday due to an ankle injury, but he was able to log a limited session Saturday to have at least a chance of suiting up Monday. If Anderson ends up being sidelined, Austin Corbett could draw the start at left guard.

Dion Dawkins OT Q

Questionable

Dawkins didn't practice at all this week due to an injury to his ribs, but he still has a chance to suit up. Per Katherine Fitzgerald of The Buffalo News, the veteran tackle was hurt in the first half of last Sunday's win over Baltimore but was able to finish out the contest. Dawkins said he'll do everything he can to be ready for Monday Night Football, so he may be a true game-time decision.

Joshua Palmer WR O

Out

Palmer exited last Sunday's win against the Ravens in the first half and wasn't able to return due to a hamstring injury. After not practicing Thursday or Friday, the Bills opted to keep him on the sidelines in Week 9, meaning Greg Dortch, Skyler Bell and/or Tyrell Shavers (knee, IR) may see WR reps behind the team's top trio at the position.

Tyrell Shavers WR O

Out

Shavers remains on the reserve/PUP list with a knee injury despite logging three consecutive full practices during Week 9 prep. The wide receiver could return to the active roster ahead of Monday night's showdown with the Vikings, but it will be contingent on the Bills creating a spot on the 53-man roster in time.

DJ Moore WR Q

Questionable

Moore has managed an AC joint sprain for most of the season, typically practicing in a non-contact jersey. He'll likely be ready for Monday's game at Minnesota, coming off a 4-82-1 receiving line (seven targets) in last week's 36-10 win over Baltimore.

Keon Coleman WR Q

Questionable

Coleman is on the injury report for the first time since Week 4, listed as a limited participant Thursday and Friday due to a shoulder injury. There's been no indication it's serious, so Coleman seems on track to play Monday night at Minnesota. Fellow Bills wideout DJ Moore (shoulder) also is gearing up to play.

Sam Franklin Jr. S Q

Questionable

questionable

Alec Anderson OT Q

Questionable

questionable

Dalton Kincaid TE Q

Questionable

Fellow pass catchers DJ Moore (shoulder) and Keon Coleman (shoulder) were also limited Thursday, so the trio's status will need to be monitored ahead of Monday night's game against the Vikings. Over his last two outings, Kincaid has managed to make his mark from a fantasy perspective by logging an 11/124/1 receiving line in that span.

Dion Dawkins OT Q

Questionable

questionable

DJ Moore WR Q

Questionable

Moore mustered some level of activity in Buffalo's first practice of Week 9 after downplaying the knee injury that forced him out late in the Week 8 win over Baltimore. He has an extra day to recover before the Bills face the Vikings on Monday Night Football. Moore has two more chances to practice without limitations and put himself in the clear to suit up.

Joshua Palmer WR Q

Questionable

The veteran wideout was injured in Sunday's win over the Ravens and was unable to return to the contest. If he's unable to play Monday night against the Vikings, Skyler Bell and Greg Dortch could see additional work on offense.

Keon Coleman WR Q

Questionable

It's a new injury for Coleman, who is on the injury report for the first time since Week 4. With both DJ Moore (knee) and Dalton Kincaid (chest) healthy last Sunday against the Ravens, Coleman caught just one pass for four yards on three targets.

Ty Johnson RB Q

Questionable

Johnson will have an extra day to rest up this week, as the Bills host the Vikings on Monday night. Buffalo's preferred pass-catching back, Johnson has rushed six times for just 10 yards through six games this season, but he has caught all 15 of his targets for 174 yards.

Jordan Hancock CB IR

Injured Reserve

Hancock has been on IR since late September while recovering from a hamstring injury he suffered in Week 2 versus Detroit. The cornerback had his 21-day practice window opened Wednesday, and if he isn't activated in that time frame, he will remain on IR for the rest of the 2026 campaign.

Dee Alford CB Q

Questionable

questionable

Greg Gaines DT Q

Questionable

questionable

Spencer Brown OT Q

Questionable

questionable

Greg Gaines DT O

Out

out

Spencer Brown OT O

Out

out

Ar'maj Reed-Adams G O

Out

inactive

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

Dee Alford CB O

Out

Alford practiced in a limited capacity Wednesday, though he didn't participate in Thursday or Friday's session. With C.J. Gardner-Johnson (suspension) also unavailable, it should mean more work for Maxwell Hairston and Damar Hamlin.

DJ Moore WR Q

Questionable

That's encouraging, but Moore's status will nonetheless be worth monitoring ahead of the Bills' Nov. 9 contest against the Vikings. Before his departure from Sunday's contest, Moore caught four of his seven targets for 82 yards and a TD.

Greg Gaines DT O

Out

Gaines was added to Friday's practice report as a limited participant due to a knee injury. He was unable to get clearance from medical staff to play Sunday and will be sidelined for the first time all season as a result. The veteran defensive tackle has tallied 11 tackles and a fumble recovery through the Bills' first six games.

Jalon Kilgore S O

Out

inactive

Joshua Palmer WR Q

Questionable

DJ Moore, Khalil Shakir, Keon Coleman and Greg Dortch are thus available to handle Buffalo's wideout duties for the remainder of the contest. Palmer's next chance to see game action will arrive Nov. 9 against the Vikings.

Mike Danna DE O

Out

inactive

Skyler Bell WR O

Out

inactive

Spencer Brown OT O

Out

Brown has been working through a back issue that he sustained in Week 5 against the Rams. The injury is severe enough that he won't suit up Sunday, so Tylan Grable figures to start at right tackle. Brown's next opportunity to play is Week 9 against the Vikings on Sunday, Nov. 9.

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

Dalton Kincaid TE Q

Questionable

Kincaid returned to a Week 6 win at Las Vegas after being evaluated for an upper-body injury. Then, coming out of a Week 7 bye, Kincaid was a limited practice participant Wednesday and Thursday, donning a no-contact jersey. He seems more likely than not to play, but fantasy managers will want to check in ahead of the 1:00 p.m. ET kickoff Sunday.

Dee Alford CB Q

Questionable

Alford opened the week as a limited practice participant before sitting out of both Thursday's and Friday's sessions. He's working through a lingering ankle injury that he sustained in Week 4 against the Patriots, but despite the consecutive DNPs, the door has not been shut on Alford suiting up for Sunday's contest. C.J. Gardner-Johnson (suspension) is not available, so If Alford is also inactive, then more snaps in the secondary would be available for Damar Hamlin, Jalon Kilgore and Maxwell Hairston.

DJ Moore WR Q

Questionable

Moore has missed the past two games and remained limited in practice this week coming out of Buffalo's bye. He failed to play through questionable designations in Weeks 5 and 6, so it remains unclear if the veteran wideout will be able to give it a go Sunday against the Ravens. If he's unable to return, Keon Coleman and Khalil Shakir would likely soak up the bulk of the snaps atop the depth chart.

Greg Gaines DT Q

Questionable

questionable

Spencer Brown OT Q

Questionable

Brown injured his back against the Rams in Week 5 but was able to play through the issue in Week 6. He was a DNP on Wednesday and Thursday before logging a limited session Friday, and if he cannot play Sunday, then Tylan Grable would be a top candidate to start at right tackle.

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

Dalton Kincaid TE Q

Questionable

Kincaid has started Week 8 prep with consecutive limited practice sessions coming out of Buffalo's Week 7 bye. The 27-year-old TE has yet to miss a game this season, but Kincaid has cooled down significantly after a scorching start, mustering 90 receiving yards over the past four games after posting 225 yards and a TD through Week 2. Kincaid will look to get back on track Sunday against the Ravens, assuming he plays through the chest injury that's limiting his practice participation.

DJ Moore WR Q

Questionable

Moore has been listed as limited both Wednesday and Thursday while practicing in a non-contact jersey. The 29-year-old wide receiver missed Buffalo's last two games prior to a Week 7 bye after having appeared in 92 consecutive regular-season games. Keon Coleman stepped up in Moore's absence and could maintain a larger role Sunday against the Ravens if Moore is ultimately sidelined or limited.

Joe Andreessen LB Q

Questionable

questionable

Ray Davis RB Q

Questionable

Davis received the day off while he was feeling under the weather, but so long as he's able to get back on the practice field Friday, he should avoid taking a designation into Sunday's game against the Ravens. While handling a backup role behind lead back James Cook this season, Davis has carried just five times for 12 yards to go with three receptions for 40 yards through Buffalo's first six contests.

Bradley Chubb LB Q

Questionable

questionable

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

Dalton Kincaid TE Q

Questionable

Before the Bills went on bye Week 7, Kincaid briefly exited a 33-30 win over the Raiders on Oct. 18 due to what the team referred to as a rib issue. His listed chest injury is presumably related and resulted in Kincaid donning a no-contact jersey during the open portion of Wednesday's practice, per Matt Parrino of The Syracuse Post-Standard. As long as the tight end is able to practice fully by the end of the week, he should be ready to handle his normal snap share in Sunday's matchup with the Ravens.

Dee Alford CB Q

Questionable

questionable

DJ Moore WR Q

Questionable

An AC joint sprain in his shoulder kept Moore from playing in Buffalo's past two games, but the wideout may be in a better spot on the health front coming out of a Week 7 bye. Per Matt Parrino of The Syracuse Post-Standard, Moore was sporting a no-contact jersey during the open portion of Wednesday's practice, so he may need to take contact at some point in the next day or two in order for the Bills to clear him to play Sunday against the Ravens.

Spencer Brown OT Q

Questionable

questionable

T.J. Sanders DT Q

Questionable

questionable

TJ Parker LB Q

Questionable

questionable

Tyrell Shavers WR O

Out

Shavers has progressed enough in his recovery from a torn ACL to return to practice, and he was a limited participant in Wednesday's session. Shavers saw his role in the Bills' offense steadily increase over the course of the 2025 season before suffering his injury in the wild-card round against the Jaguars in January. His next opportunity to play is Week 9 against the Vikings on Monday, Nov. 9.

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

Sam Franklin Jr. S SUS

Suspension

The suspension stems from Franklin allegedly spitting at an opponent late in the fourth quarter during a successful extra-point attempt by the Raiders. The veteran defensive back has denied the allegation by the league and will appeal the ruling, per Adam Schefter of ESPN. Franklin has played solely on special teams this season, but with C.J. Gardner-Johnson also handed a one-game suspension, the Bills' secondary could be thin for their Week 8 game against the Ravens on Sunday, Nov. 1.

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

DJ Moore WR Q

Questionable

questionable

Ed Oliver DT Q

Questionable

questionable

C.J. Gardner-Johnson S SUS

Suspension

reserve-sus

Ar'maj Reed-Adams G O

Out

inactive

Dalton Kincaid TE Q

Questionable

Kincaid was evaluated by trainers in the blue medical tent late in the third quarter before heading to the locker room, where he will undergo further tests to determine whether he can return to Sunday's game. Dawson Knox and Jackson Hawes should both see a bump in offensive snaps for as long as Kincaid is sidelined.

DJ Moore WR O

Out

After sitting out a Week 5 overtime win at the Rams, Moore managed just one limited practice (Friday) this week, and he donned a red non-contact jersey while doing so. Per Joe Buscaglia of The Athletic, Moore again didn't log much activity during pregame warmups for a second straight week, forecasting another absence was likely. With Moore's status now clarified, Khalil Shakir, Keon Coleman and Joshua Palmer (shoulder) should earn most of the WR reps in the Bills offense in Week 6.

Ed Oliver DT O

Out

Oliver will miss a second consecutive game due to the knee injury he sustained during the Bills' Week 4 loss to the Patriots. The defensive tackle will once again be replaced by a mixture of Greg Gaines, DeWayne Carter and T.J. Sanders.

Jude Bowry OT O

Out

inactive

Mike Danna DE O

Out

inactive

Dee Alford CB Q

Questionable

Alford was unable to play against the Rams on Monday due to an ankle injury. He was limited in all three Week 6 practices, and his official status for Sunday's game may not be known until about 90 minutes before the 4:25 p.m. ET kickoff, when the Bills announce their list of inactive players. Damar Hamlin would see additional work at the slot corner position if Alford is not cleared to play.

DJ Moore WR Q

Questionable

Moore returned to practice Friday in a non-contact jersey, potentially setting up a game-time decision ahead of Sunday's 4:25 p.m. ET kickoff. Fellow Bills wideout Joshua Palmer (shoulder) also is listed as questionable, after both Moore and Palmer missed an overtime win at Los Angeles in Week 5. Keon Coleman, Khalil Shakir and Skyler Bell handled nearly all of the WR routes last week.

Ed Oliver DT Q

Questionable

Oliver opened the week with consecutive DNPs before logging a limited practice Friday, which was enough for the veteran defensive lineman to be tagged as questionable. If Oliver is ruled out for a third straight game, then Greg Gaines and DeWayne Carter would once again step into larger roles on the Bills' defensive line.

Joshua Palmer WR Q

Questionable

Both wideouts missed Monday's win over the Rams, in which each of Keon Coleman, Khalil Shakir and Skyler Bell topped 60 percent route share, though many of those routes were on plays that ended up being Josh Allen scrambles. Bell likely will lose the most playing time if Moore and/or Palmer returns this week.

DJ Moore WR Q

Questionable

While Moore was in attendance for practice, he was sporting a red no-contact jersey and didn't take part in stretching or drills with his healthy teammates before heading inside to presumably get in some individual work, per Matt Parrino of The Syracuse Post-Standard. After sitting out Monday's overtime win over the Rams and having gone down as a non-participant on the Bills' first two Week 6 practice report, Moore looks to be trending toward missing another game Sunday in Las Vegas.

DJ Moore WR Q

Questionable

The Bills conducted a walkthrough Wednesday after playing Monday night, but Moore would not have gotten any work in had the Bills decided to practice. Moore will have a couple chances to practice before the week comes to a close, but with Buffalo on bye in Week 7, the team could decide to hold him out again Sunday in an effort to maximize the recovery time.

Ed Oliver DT Q

Questionable

Oliver hasn't practiced since sustaining the knee injury in the Bills' Week 4 loss to the Patriots. The Bills have a bye coming up Week 7, so it wouldn't be surprising if Oliver ended up missing a second straight game this Sunday against the Raiders in order to get extra time to heal up from his knee injury.

Joshua Palmer WR Q

Questionable

Palmer suffered a shoulder injury during practice and was ultimately unavailable for Buffalo's Week 5 win over the Rams on Monday Night Football. Although the team didn't officially practice Wednesday, the wide receiver's listing as a limited participant is a positive sign. Palmer will have two more chances to officially practice in full prior to Sunday's matchup with the Raiders.

T.J. Sanders DT Q

Questionable

questionable

Ty Johnson RB Q

Questionable

Johnson reeled in all four of his targets for 72 yards during Monday night's 37-34 overtime win against the Rams, but he may have picked up a hamstring injury in the process. The running back's ability to be limited Wednesday is a positive sign, and he'll have two more chances to log a full practice and erase any concern about his availability for Sunday's contest versus Las Vegas.

Dee Alford CB Q

Questionable

questionable

DJ Moore WR Q

Questionable

questionable

Ed Oliver DT Q

Questionable

questionable

Joshua Palmer WR Q

Questionable

questionable

Landon Jackson DE Q

Questionable

questionable

Ar'maj Reed-Adams G O

Out

inactive

Dee Alford CB O

Out

Alford drew the questionable tag for Monday night's game after logging a limited practice Saturday, but he'll end up missing his first game of the season due to an ankle injury that he sustained against the Patriots in Week 4. Damar Hamlin should see some more defensive snaps at the slot corner position in Alford's absence.

DJ Moore WR O

Out

After suffering a shoulder injury in Week 4, Moore wasn't expected to be tending to a long-term issue, and head coach Joe Brady told Katherine Fitzgerald of The Buffalo News on Thursday that the wide receiver was "going to be able to do everything he can to be able to rock this week." Moore then managed just one limited session (Saturday) during Week 5 prep, which wasn't enough for him to gain clearance to play Monday. With both Moore and Joshua Palmer (shoulder) unavailable, Khalil Shakir, Keon Coleman, Greg Dortch, Skyler Bell and Trent Sherfield will handle WR reps for the Bills.

Ed Oliver DT O

Out

inactive

Joshua Palmer WR O

Out

inactive

Jude Bowry OT O

Out

inactive

Landon Jackson DE O

Out

Jackson was initially listed as questionable due to a knee injury, which is severe enough for the second-year pro to miss his first game of the regular season. Greg Gaines and DeWayne Carter are in line for more rotational reps on the Bills' defensive line due to Jackson's absence.

Spencer Brown OT Q

Questionable

Brown sustained a back injury early in the contest, and his night has now officially come to a premature end. Tylan Grable will continue to operate as the team's starting right tackle in Brown's place.

Dee Alford CB Q

Questionable

Alford sustained an ankle injury during the Bills' Week 4 loss to the Patriots. He was a DNP in each of the first two practices of Week 5 prep, but he earned the questionable tag after getting back to the field for Saturday's session. Damar Hamlin would likely operate as the Bills' slot cornerback if Alford is unable to play Monday.

DJ Moore WR Q

Questionable

Moore was able to participate in Saturday's practice in a limited capacity after being sidelined for the first two sessions of Week 5 prep, and that's enough for the veteran wide receiver to draw the questionable tag for Monday night's contest. Joshua Palmer (shoulder) has already been ruled out, so if Moore is also sidelined, then Khalil Shakir and Keon Coleman would operate as the top wide receivers for Buffalo.

Ed Oliver DT O

Out

The veteran defensive lineman will miss his second game of the season, this time due to a knee injury that he picked up during the Bills' Week 4 loss to the Patriots. DeWayne Carter and Greg Gaines should both see more defensive snaps in the absence of Oliver, whose next chance to play is Week 6 against the Raiders on Sunday, Oct. 18.

Joshua Palmer WR O

Out

Palmer popped up on Friday's injury report as a limited participant due to a shoulder issue, which appears to be severe enough for him to miss his first game of the season. With DJ Moore (shoulder) listed as questionable, the Bills' top pass catching options could be Khalil Shakir, Keon Coleman and Dalton Kincaid, and rookie Skyler Bell is expected to make his NFL debut after being a healthy scratch in each of the first four games of the regular season, per Joe Buscaglia of The Athletic. Palmer's next chance to play is Week 6 against the Raiders on Sunday, Oct. 18.

Landon Jackson DE Q

Questionable

Jackson's practice reps were limited due to a knee injury, and his status for Monday's game may not be officially known until the Bills announce their list of inactive players approximately 90 minutes before the 8:15 p.m. ET kickoff. Ed Oliver (knee) has already been ruled out, so DeWayne Carter and Greg Gaines would both be in line for even more defensive snaps if Jackson is not cleared to play.

DJ Moore WR Q

Questionable

With back-to-back absences, Moore isn't looking great for Sunday's game at the Rams, though he'll still have one more chance Saturday to practice. If he doesn't end up playing, Keon Coleman and Joshua Palmer will be the top candidates to replace Moore's snaps, with slot receiver Khalil Shakir and tight end Dalton Kincaid potentially helping to pick up the slack in terms of target volume.

Christian Benford CB Q

Questionable

Benford suffered a toe injury against the Chargers in Week 3 and didn't practice at all last week. After missing Sunday's matchup against the Patriots, the veteran cornerback was able to return to practice, albeit in a limited capacity, Thursday. The Bills play Monday against the Rams, so Benford will have two more days to try to ramp up to full practice participation and avoid an injury designation ahead of that contest.

Dee Alford CB Q

Questionable

Per Lysowski, coach Joe Brady said Thursday that the ankle injury Alford sustained in Week 4 versus New England is not expected to be a long-term problem. The Bills' matchup against the Rams in Week 5 won't kick off until Monday, so Alford will have an extra day to potentially get healthy in anticipation of that contest.

DJ Moore WR Q

Questionable

Moore has not been ruled out for the Week 5 matchup against the Rams, but it seems he's got an uphill battle ahead of him. He aggravated his shoulder injury in the Week 4 loss to the Patriots and did not return to action. He may get some work in later in Thursday's practice, but the official injury report will tell the tale.

Ed Oliver DT Q

Questionable

Per Lysowski, coach Joe Brady said Thursday that the knee injury Oliver suffered during Sunday's game versus the Patriots is not believed to be a long-term issue. Still, his activity at practice will be worth monitoring as the Bills continue to prepare for a Week 5 matchup against the Rams on Monday.

Landon Jackson DE Q

Questionable

questionable

Christian Benford CB Q

Questionable

questionable

T.J. Sanders DT Q

Questionable

questionable

Dee Alford CB Q

Questionable

Alford sustained the injury in the second half of Sunday's game, and he's being evaluated by trainers to determine whether he can return. Davison Igbinosun should see more defensive snaps in Alford's absence.

DJ Moore WR Q

Questionable

Moore exited Sunday's loss to the Patriots after aggravating a previous shoulder injury. He isn't expected to miss significant time, though it remains to be seen if Moore will play against the Rams in Week 5. The 29-year-old wide receiver has suited up for 92 consecutive regular-season games dating back to the 2020 season.

Ed Oliver DT Q

Questionable

With Oliver being evaluated by medical staff and T.J. Sanders (appendix) inactive, the Bills will lean more heavily on DeWayne Carter, Landon Jackson and Greg Gaines on defense.

Te'Cory Couch CB Q

Questionable

Couch was a practice-squad elevation for Week 4. He was slated to potentially pick up some work on defense with Christian Benford (toe) inactive, but now Couch is probably done for the day. With that said, Couch's likely absence will primarily impact Buffalo's special-teams unit.

Ar'maj Reed-Adams G O

Out

An elbow injury limited Reed-Adams' practice participation all week, and he has not been given clearance by medical staff to play Sunday. The rookie seventh-rounder's next chance to suit up is Week 4 against the Patriots on Sunday, Oct. 4.

Christian Benford CB Q

Questionable

Benford left the game in the third quarter due to a toe injury, which is severe enough for him to be sidelined for the rest of Sunday's contest. Te'Cory Couch and Davison Igbinosun will continue to operate in elevated roles in Benford's absence.

Jalon Kilgore S O

Out

inactive

Jude Bowry OT O

Out

inactive

Mike Danna DE O

Out

inactive

Skyler Bell WR O

Out

With Keon Coleman (ankle) and DJ Moore (shoulder) having been in jeopardy of missing Sunday's contest, there was a chance Bell would be needed to suit up. However, Coleman and Moore are good to go, meaning Bell's next chance to get on the field will come in Week 4 for the AFC East clash with the Patriots.

T.J. Sanders DT O

Out

inactive

Jordan Hancock CB IR

Injured Reserve

Hancock likely suffered his hamstring injury in the Bills' Week 2 win over the Lions. The issue appears to be significant, leading the team to move Hancock to IR. The defensive back will need to miss at least four games before becoming eligible to return to the Bills' active roster. The team signed Greg Dortch from the practice squad to the active roster in a corresponding move.

DJ Moore WR Q

Questionable

Moore carried once for minus-1 yard and didn't draw a target on his 23 snaps before exiting Thursday's contest late in the second quarter. Keon Coleman (55 snaps, 6-63-0 line on six targets) saw a boosted profile on offense in Moore's absence, but Coleman could fade into more of a tertiary role in the passing game if Moore is able to play through the shoulder injury during the Bills' Week 3 matchup with the Chargers. Rapoport relays that Moore is expected to practice next week, and the Bills will see how his shoulder responds before his status for next Sunday's contest is clarified.

Ed Oliver DT O

Out

Oliver did not play in the Bills' 41-31 win over the Lions on Thursday after sustaining a hip injury during pregame warmups. The veteran defensive lineman's practice participation during the upcoming week will ultimately determine whether he'll be available for Week 3. DeWayne Carter was the defensive lineman that saw his defensive snap count jump the most from Week 1 to Week 2 in Oliver's absence.

Ar'maj Reed-Adams G O

Out

inactive

Jalon Kilgore S O

Out

inactive

Jude Bowry OT O

Out

inactive

Skyler Bell WR O

Out

Bell will be inactive for another contest after being a healthy scratch for Sunday's 36-31 win over the Texans. His next opportunity to get on the field will come in Week 3 versus the Chargers.

T.J. Sanders DT O

Out

Sanders was sidelined by a knee injury in Week 1 and then came down with an illness earlier in the week, and the combination of both leaves him unavailable for Week 2. In his absence, 2024 third-rounder DeWayne Carter figures to continue to see increased work on the defensive line.

Ty Johnson RB O

Out

Despite being listed as limited on all three of the Bills' Week 2 injury reports, Johnson will continue to don street clothes on game days due to a hamstring issue that has bothered him since at least Aug. 24. In Johnson's absence, Ray Davis will continue to garner RB reps that don't go to starter James Cook, while Frank Gore is on hand in case one of those two leaves the game for any reason.

Cole Bishop S Q

Questionable

Bishop was listed as a limited practice participant on all three injury reports due to a groin injury, and his status for Thursday's game may not be officially known until about 90 minutes before the 8:15 p.m. ET kickoff. Damar Hamlin would likely draw the start at safety alongside C.J. Gardner-Johnson if Bishop is not cleared to play.

T.J. Sanders DT Q

Questionable

Sanders is still battling the illness and knee injury that forced him to miss the team's Week 1 win over the Texans. If he ends up being good to go on Thursday, the 23-year-old will be in line to serve as one of the Bills' starting defensive linemen for the matchup versus the Lions.

Ty Johnson RB Q

Questionable

Johnson sat out the Week 1 victory over the Texans. He returned to a limited practice Tuesday, but he's not quite in the clear yet, and his status will probably come down to the wire for the primetime game Thursday. No Buffalo running back has much value outside of insurance behind bell-cow back James Cook, and now Frank Gore has had a chance to enter the mix as yet another option in the Buffalo backfield.

T.J. Sanders DT Q

Questionable

questionable

Ty Johnson RB Q

Questionable

After missing the Bills' first two practices of Week 1, Johnson returned to the field Friday as a limited participant and took a questionable tag into Sunday's season opener versus the Texans. Johnson ultimately was inactive for the 36-31 win, but he'll have a stronger chance of making his 2026 debut Thursday against the Lions if he can upgrade to full participation in practice at some point over the next two days.

Dorian Strong CB O

Out

nfi-r

Tyrell Shavers WR O

Out

out

Jedrick Wills Jr. OT Q

Questionable

questionable

Khalil Shakir WR Q

Questionable

Since making an appearance preseason Week 1 on Aug. 15, Shakir has been sidelined due to an undisclosed injury, including no activity at Tuesday's practice. The Bills will post their first Week 1 injury report next Wednesday, and how he's listed then will provide a sense for his status ahead of the regular-season opener.

Keon Coleman WR Q

Questionable

Coleman sustained a sprained right foot/toe in the Bills' preseason opener Aug. 15, but he ditched his low walking boot as of last Thursday and now appears set to mix back into drills. The extent of his activity Tuesday isn't known, but he still has nearly two weeks to get healthy ahead of a Week 1 road matchup with the Texans on Sunday, Sept. 13.

Ty Johnson RB Q

Questionable

Johnson exited practice in early August and has been dealing with some sort of issue in his leg for the better part of a full month now. He resumed running and sprinting last week. Turning 29 later this month, Johnson has carved out a role on game days with the Bills, but he's more of a nuisance than anything in fantasy. Even if James Cook were to go down with an injury, Johnson's role likely wouldn't change all that much, as Ray Davis is Cook's more direct backup as a rusher. Johnson has averaged just 3.9 touches per game over his 34 regular-season appearances dating back to the start of the 2024 campaign.

Tyrell Shavers WR O

Out

Shavers missed the entirety of training camp and the preseason while he continues to recover from a torn ACL that he suffered in the team's 27-24 win over the Jaguars in the 2025 wild-card round. The wide receiver will now be forced to sit out at least four contests to begin the regular season, and the earliest he'll be able to make his season debut is Week 5 against the Rams on Monday Night Football.

Zane Durant DT IR

Injured Reserve

Durant compiled six total tackles (three solo) during the preseason, but he appears to have picked up an undisclosed injury at some point along the way. As a result, the 2026 fifth-round pick will be forced to miss at least four regular-season contests to open his rookie campaign.

Keon Coleman WR Q

Questionable

Coleman has been tending to a sprained right foot/toe that he sustained in the Bills' exhibition opener, which forced him to don a low walking boot since then. Shedding the boot is a positive sign in his recovery effort, but Coleman will join Khalil Shakir (undisclosed) and Tyrell Shavers (knee, active/PUP) as injured Buffalo wide receivers that won't suit up Thursday. Coleman will turn his focus to getting completely healthy for the team's regular-season opener Sunday, Sept. 13 at Houston.

Khalil Shakir WR Q

Questionable

Shakir now will miss a second consecutive exhibition due to an undisclosed injury that has sidelined him for the past week. Fellow position mates Keon Coleman (foot/toe) and Tyrell Shavers (knee, active/PUP) also aren't suited up Thursday. Shakir will set his sights on getting healthy for the Bills' Week 1 road matchup with the Texans on Sunday, Sept. 13.

Terrel Bernard LB Q

Questionable

questionable

Ty Johnson RB Q

Questionable

Though Johnson hasn't practiced in more than two weeks while nursing a lower-leg injury and looks unlikely to play in Thursday's preseason finale versus the Steelers, Brady noted that the running back is "in a good head space" and could still be available for Week 1 in Houston. If Johnson ends up being sidelined to begin the regular season, however, lead back James Cook could take on a heightened role on passing downs.

Jude Bowry OT Q

Questionable

Bowry was spotted with a boot on his left foot at Monday's practice, so his availability for Thursday's preseason finale against the Steelers is definitely up in the air. The 23-year-old was selected in the fourth round of this year's draft, and when healthy, he's expected to operate as a reserve option behind Dion Dawkins and Spencer Brown at offensive tackle this season.

Connor McGovern C Q

Questionable

questionable

Demetrius Flannigan-Fowles LB IR

Injured Reserve

ir

Phidarian Mathis DT SUS

Suspension

reserve-sus

Chase Lundt OT Q

Questionable

Lundt ended the 2025 season with just eight total snaps for the Bills. The 2025 sixth-rounder is battling with Jude Bowry, Travis Clayton, Nick Broeker and Austin Corbett for a chance at the 53-man roster. With the Bills keeping nine offensive linemen on the initial 2025 roster, two of the four players will likely not make the 2026 cut.

Ben VanSumeren FB Q

Questionable

VanSumeren has fully recovered from the torn patella tendon he suffered last September with the Eagles. The 26-year-old is expected to serve as the Bills' primary fullback during the upcoming campaign.

Michael Hoecht DE Q

Questionable

Hoecht tore his right Achilles during the Bills' Week 9 contest against the Chiefs. That was just his second appearance of the 2025 regular season after he missed the first six games while serving a suspension. He's drawn praise from his teammates and coaching staff for his approach to his rehab, and Hoecht is hoping to be available for the Bills' regular-season opener against the Texans on Sunday, Sept. 13.

Tyrell Shavers WR O

Out

Shavers tore his ACL during the Bills' 27-24 win over the Jaguars in the 2025 wild-card round. Shavers played in all 17 regular-season games during the 2025 season, catching 15-of-23 targets for 245 yards and one touchdown. It remains to be seen where the 26-year-old fits into the 2026 Bills' offensive scheme, as Joshua Palmer is returning from an ankle issue, and the team drafted Skyler Bell in the fourth round of the 2026 draft.

Dorian Strong CB O

Out

Strong had a productive rookie season, logging reps at outside cornerback throughout the first four weeks of the 2025 season before suffering a career-altering neck injury. The 2025 sixth-round pick was seen at OTAs, but he's not expected to play in 2026 due to the severity of the neck issue. Strong cleared waivers, allowing the Bills to keep him on the roster as he works towards a possible return in 2027.